Antioxidant BHT 264
CAS:128-37-0
Purity:99%
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Quality products make an important contribution to long-term revenue and profitability. Factory supply Mavacamten 1642288-47-8 with sufficient production capacity
MYK-461 is a drug used to treat obstructive hypertrophic cardiomyopathy as a cardiac myosin inhibitor.?Mavacamten is used to treat adults with symptomatic obstructive hypertrophic cardiomyopathy. It is used to treat symptomatic obstructive hypertrophic cardiomyopathy (HCM).
6-chloro-3-isopropylpyrimidine-2,4(1H,3H)-dione
(S)-1-phenyl-ethylamine
![6-{[(1S)-1-phenylethyl]amino}-3-(propan-2-yl)-1,2,3,4- tetrahydropyrimidine-2,4-dione](/upload/2026/7/957ea9da-83c7-4a82-8329-15c5b736dade.png)
6-{[(1S)-1-phenylethyl]amino}-3-(propan-2-yl)-1,2,3,4- tetrahydropyrimidine-2,4-dione
| Conditions | Yield |
|---|---|
|
In
1,4-dioxane;
at 90 ℃;
|
69% |
|
In
1,4-dioxane;
for 24h;
|
69% |
|
at 100 ℃;
for 5h;
Temperature;
Inert atmosphere;
|
53% |
1-isopropylpyrimidine-2,4,6(1H,3H,5H)trione
6-{[(1S)-1-phenylethyl]amino}-3-(propan-2-yl)-1,2,3,4- tetrahydropyrimidine-2,4-dione
| Conditions | Yield |
|---|---|
|
Multi-step reaction with 2 steps
1: N-benzyl-N,N,N-triethylammonium chloride; trichlorophosphate / 50 °C / Inert atmosphere
2: 1,4-dioxane / 90 °C
With
N-benzyl-N,N,N-triethylammonium chloride; trichlorophosphate;
In
1,4-dioxane;
|
The CAS number of 6-{[(1S)-1-phenylethyl]amino}-3-(propan-2-yl)-1,2,3,4- tetrahydropyrimidine-2,4-dione is 1642288-47-8.
More information of 6-{[(1S)-1-phenylethyl]amino}-3-(propan-2-yl)-1,2,3,4- tetrahydropyrimidine-2,4-dione 1642288-47-8 are:
|
CAS Number |
1642288-47-8 |
|
Density |
1.19±0.1 g/cm3(Predicted) |
Synonyms for 6-{[(1S)-1-phenylethyl]amino}-3-(propan-2-yl)-1,2,3,4- tetrahydropyrimidine-2,4-dione 1642288-47-8:
The chemical formula of 6-{[(1S)-1-phenylethyl]amino}-3-(propan-2-yl)-1,2,3,4- tetrahydropyrimidine-2,4-dione is C15H19N3O2 which containing 15 Carbon atoms,19 Hydrogen atoms,3 Nitrogen atoms and 2 Oxygen atoms,and the molecular weight of 6-{[(1S)-1-phenylethyl]amino}-3-(propan-2-yl)-1,2,3,4- tetrahydropyrimidine-2,4-dione is 273.335.
Mavacamten（MYK-461）is a first-in-class allosteric inhibitor of cardiac myosin that promises to provide clinicians with targeted therapy for these patients. It is a mechanistically novel small molecule that acts on the sarcolemma to specifically inhibit contractility and has been proposed as a treatment for HCM.
Relevant articles related to 6-{[(1S)-1-phenylethyl]amino}-3-(propan-2-yl)-1,2,3,4- tetrahydropyrimidine-2,4-dione:
|
Article |
Source |
|
MAVACAMTEN FOR USE IN THE TREATMENT OF HYPERTROPHIC CARDIOMYOPATHY |
- Paragraph 0193, (2019/02/15) |
Huaihua Yuanyanda Biotechnology Co., Ltd is a quality supplier of 6-{[(1S)-1-phenylethyl]amino}-3-(propan-2-yl)-1,2,3,4- tetrahydropyrimidine-2,4-dione. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on 6-{[(1S)-1-phenylethyl]amino}-3-(propan-2-yl)-1,2,3,4- tetrahydropyrimidine-2,4-dione 1642288-47-8.
