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High quality purity >99% Metronidazole 443-48-1 for sale We supply high quality Metronidazole (CAS 443-48-1), in stock, factory directly supply to clients, lower prices, more competitiveness.
Metronidazole is white to slightly yellow crystalline powder, while it's Molecular Formula is C6H9N3O3. Metronidazole, is an antibiotic and antiprotozoal agent. It is mainly used to treat or prevent systemic or local infections caused by anaerobic bacteria, such as anaerobic bacterial infections in the abdominal cavity, digestive tract, female reproductive system, lower respiratory tract, skin and soft tissues, bones and joints, etc. Inflammation, meningeal infections, and colitis caused by antibiotic use are also effective. Tetanus is often treated with tetanus antitoxin (TAT). It can also be used for oral anaerobic infection. On October 27, 2017, the list of carcinogens published by the World Health Organization's International Agency for Research on Cancer was preliminarily sorted for reference, and metronidazole was included in the list of class 2B carcinogens. In January 2020, metronidazole was selected into the second batch of national centralized drug procurement list.
The CAS number of Metronidazole is 443-48-1.
More information of Metronidazole 443-48-1 are:
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Synonyms |
Bexon;Vagilen;1-(2-Hydroxy-1-ethyl)-2-methyl-5-nitroimidazole;Meronidal;Trikojol;Novonidazol;RP 8823;Eumin;Metronidazole (JP14/USP);Bayer 5360;Trichopol;Trichex;Sanatrichom;Nalox;Trikamon;1-Hydroxyethyl-2-methyl-5-nitroimidazole;Metric 21;Monasin;Giatricol;Orvagil;MTZ;Metronidazol;NIDA;Trichazol;Flagyl;Deflamon;Entizol;2-Methyl-1-(2-hydroxyethyl)-5-nitroimidazole;1-(.beta.-Hydroxyethyl)-2-methyl-5-nitroimidazole;Trikozol;1H-Imidazole-1-ethanol,2-methyl-5-nitro-;1-(.beta.-Ethylol)-2-methyl-5-nitro-3-azapyrrole;Klion;Arilin;Clont;Trimeks;Danizol;Efloran;Methronidazole;Trivazol;Acromona;1-(2-Hydroxyethyl)-2-methyl-5-nitroimidazole;Flagesol;Tricocet;Monagyl;Vertisal;Prestwick_334;Klont;Flegyl;Tricowas B;Trichomonacid pharmachim;Trichopal;Trichocide;Flagemona;Trichomol;Metronidaz;1H-Imidazole-1-ethanol, 2-methyl-5-nitro-;1-(β-Ethylol)-2-methyl-5-nitro-3-azapyrrole;1-(β-Hydroxyethyl)-2-methyl-5-nitroimidazole;NSC-50364;1-(β-Oxyethyl)-2-methyl-5-nitroimidaz-ole;2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethan-1-ol; |
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CAS Number |
443-48-1 |
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Molecular Formula |
C6H9N3O3 |
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Molecular Weight |
171.156 |
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Density |
1.45 g/cm3 |
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Melting Point |
159-161 °C(lit.) |
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Boiling Point |
405.4 °C at 760 mmHg |
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Flash Point |
199 °C |
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HS CODE |
29332990 |
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PSA |
83.87000 |
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LogP |
0.61520 |
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Pka |
pKa 2.62(H2O,t =25±0.2,Iundefined) (Uncertain) |
Metronidazole is a nitroimidazole antibiotic first isolated in the 1950s. Many nitroimidazoles were being studied at the time, as the class was found to have trichomonacidal properties. Metronidazole was of particular interest due to its high activity against Trichomonas vaginalis and Entamoeba histolytica both in vitro and in vivo as well as clinical activity against many anaerobic pathogens including Gram-positive and Gramnegative bacteria and Giardia lamblia. Metronidazole is often used clinically for intra-abdominal infections and is the firstline treatment for Clostridium difficile–associated diarrhea.
InChI:InChI=1/C6H9N3O3/c1-5-7-6(9(11)12)4-8(5)2-3-10/h4,10H,2-3H2,1H3
Articles related to Metronidazole:
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Article |
Source |
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SYNTHESIS OF METRONIDAZOLE FROM ETHYLENEDIAMINE |
Kraft, M. Ya.,Kochergin, P. M.,Tsyganova, A. M.,Shlikhunova, V. S. , p. 861 - 863 (1989) |
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Method for synthesizing metronidazole under catalysis of solid acid |
- Paragraph 0029-0058, (2019/09/05) |
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